Publications

These are publications from work undertaken by Frontier Science (Scotland).

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A Sonnenblick;  D Agbor-Tarh; I Bradbury; S Di Cosimo; J A Zujewski; H A Azim Jr; J Judith; M Andersson; T Cufer; S Simon; P Salman; M Toi; L Harris; J Gralow; A Moreno-Aspitia; M. Piccart; E. de Azambuja; K Macoon;  May, 2017

Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2-Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial

Journal of Clinical Oncology,  Volume 35, Issue 13, 1421-1429, doi:10.1200/JCO.2016.69.7722


G von Minckwitz;  M Procter; E. de Azambuja; D Zardavas; M Benyunes; G Viale; T M Suter; A Arahmani; N Rouchet; E Clark; A Knott; I Lang; C Levy; D Yardley; J Bines; RD Gelber; M. Piccart; J Baselga;  June 5, 2017

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer

The New England Journal of Medicine,  doi: 10.1056/NEJMoa1703643


D Fumagalli;  D Venet; M Ignatiadis; H A Azim Jr; M Maetens; F Rothé; R Salgado; I Bradbury; L Pusztai; N Harbeck; H Gomez; T W Chang; M Coccia-Portugal; S Di Cosimo; E. de Azambuja; L de la Pena; P Nuciforo; J C Brase; J Huober; J Baselga; M. Piccart; S Loi; C Sotiriou;  2017

RNA Sequencing to Predict Response to Neoadjuvant Anti-HER2 Therapy: A Secondary Analysis of the NeoALTTO Randomized Clinical Trial

JAMA Oncol,  Pages 227-234, 3(2) doi:10.1001/jamaoncol.2016.3824


E McFadden;  2016

Data Management and Coordination

Wiley StatsRef: Statistics Reference online,  1-14 doi:10.1002/9781118445112.stat04933.pub2


I Gingras;  E Holmes; E. de Azambuja; D H A Nguyen; M Izquierdo; J A Zujewski; M Inbar; B Naume; G Tomasello; J Gralow; AC Wolff; L Harris; M Gnant; A Moreno-Aspitia; M. Piccart; H. A. Azim Jr;  2017

Regional Nodal Irradiation After Breast Conserving Surgery for Early HER2-Positive Breast Cancer: Results of a Subanalysis from the ALTTO Trial

Journal of the National Cancer Institute,  Volume 109, Issue 8, doi: 10.1093/jnci/djw331


W Shi;  T Jiang; P Nuciforo; C Hatzis; E Holmes; N Harbeck; C Sotiriou; L Peña; S Loi; D Rosa; S Chia; A Wardley; T Ueno; J Rossari; H. Eidtmann; A Armour; M Piccart-Gebhart; D L Rimm; J Baselga; L Pusztai;  2017

Pathway level alterations rather than mutations in single genes predict response to HER2 targeted therapies in the neo-ALTTO trial

Annals of Oncology,  Volume 28, Issue 1, p128-135, doi:10.1093/annonc/mdw434


D Cameron;  M Piccart-Gebhart; RD Gelber; M Procter; A Goldhirsch; E. de Azambuja; G Castro Jr; M Untch; I Smith; L Gianni; J Baselga; N Al-Sakaff; S Laver; E McFadden; B Leyland-Jones; R Bell; M Dowsett; C Jackisch;  February 16, 2017

11 years’ follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial

www.thelancet.com,  doi:10.1016/S0140-6736(16)32616-2


S Di Cosimo;  C Campbell; H A Hazim; G Curigliano; R Crescenzo; L de la Pena; M Piccart-Gebhart; H. Eidtmann; J Baselga; E. de Azambuja;  2016

Breast ultrasound and mammography and response to neoadjuvant lapatinib, trastuzumab and their combination in HER2 positive breast cancer: Results from Neo-ALTTO (BIG 1-06)

Cancer Research,  Volume 76, Issue 4, doi:10.1158/1538-7445.SABCS15-P6-01-04


E McFadden;  S Bashir; S Canham; J Darbyshire; P Davidson; S Day; S Emery; J Pater; S Rudkin; M Stead; J Brown;  2015

The impact of registration of clinical trials units: the UK experience

Clinical Trials,  Volume 12, Issue 2, Pages 166-173, doi:10.1177/1740774514561242


O Metzger-Filho;  E. de Azambuja; M Procter; M Krieguer; I Smith; J Baselga; D Cameron; M Untch; C Jackisch; R Bell; L Gianni; A Goldhirsch; M. Piccart; RD Gelber; HERA Study Team;  2016

Trastuzumab Re-Treatment Following Adjuvant Trastuzumab and the Importance of Distant Disease-Free Interval: the HERA Trial Experience

Breast Cancer Research and Treatment,  Volume 155, Issue 1, Pages 127-132,doi: 10.1007%2Fs10549-015-3656-0


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